Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Antibacterial - PptT inhibitor 8918

PptT inhibitor 8918

CAS No. 65009-19-0

PptT inhibitor 8918( Compound 8918 )

Catalog No. M15469 CAS No. 65009-19-0

PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    PptT inhibitor 8918
  • Note
    Research use only, not for human use.
  • Brief Description
    PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM).
  • Description
    PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM), shows an MIC90 of 3.1 uM against Mtb H37Rv; also exhibits MIC90s ranged from 0.56-3.0 uM (median 1.5 uM) against 29 clinical isolates of Mtb; inhibits growth of WT Mtb, but not of the pptT mutant W170S or WT Mtb expressing the pptT W170S mutant; kills Mycobacterium tuberculosis (Mtb) by binding and partially inhibiting PptT.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Compound 8918
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    65009-19-0
  • Formula Weight
    262.357
  • Molecular Formula
    C14H22N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Amidino-urea 1-[(2,6-diethylphenyl)-3-N-ethylcarbamimodoyl]urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ballinger E, et al. Science. 2019 Feb 1;363(6426). pii: eaau8959. doi: 10.1126/science.aau8959.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Cefprozil hydrate

    Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic.

  • Captan

    Captan (Aacaptan) is a phthalimide fungicide that disrupts oocyte development.Captan is cytotoxic to mammalian cells and enhances the cytotoxicity of hydrogen peroxide.

  • Phanquinone

    Phanquinone is active against a wide range of Gram-positive and Gram-negative organisms.?

Sign In Join Free